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InChi: InChI=1S/C18H18N2O4/c21-15(19-24)10-2-1-3-11-20-17(22)13-8-4-6-12-7-5-9-14(16(12)13)18(20)23/h4-9
YS-49 monohydrate Size:2 mg solid InChi: InChI=1S/C18H18N2O4/c21-15(19-24)10-2-1-3-11-20-17(22)13-8-4-6-12-7-5-9-14(16(12)13)18(20)23/h4-9YS 49 is an anti inflammatory agent and activator of PI3K Akt signaling. YS 49 regulates angiotensin II stimulated ROS production, JNK phosphorylation and vascular smooth muscle cell proliferation via the induction of heme oxygenase 1. YS 49 induced HO 1 protein production in a dose and time dependent manner in VSMCs. Treatment with YS 49 significantly and dose dependently inhibited Ang II induced VSMC proliferation, ROS production, and
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